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Yersinia pestis KIM encoded proteins were compared with Escherichia coli K12, Salmonella enterica serovar Typhi CT18, and Salmonella typhimurium LT2 SGSC1412 proteins.
The publicly available sequences and annotations from NCBI were used. Our software package PyMood was used for the comparative analysis and data visualization.
We identified 2400 proteins evolving with a consistent rate among all four genomes. There are 156 Yersinia pestis proteins absent in Escherichia coli, but present and evolving with a consistent rate in the other three genomes. For 1070 Yersinia pestis proteins we have not found homologs in Escherichia coli, Salmonella enterica serovar Typhi, and Salmonella typhimurium (e > 10 -8).
We found 93 genes common only between Yersinia pestis and E. coli, 52 genes common only between Yersinia pestis and Salmonella typhimurium, and 26 genes common only between Yersinia pestis and Salmonella enterica serovar Typhi.
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